Dosing and Administration shrinking drugs: take 1 table. Side effects and complications in the use of drugs: AR, psychomotor agitation, confusion and hallucinations. Indications for use drugs: Endometriosis - treatment of symptoms associated with endometriosis and / or suspension or reduction of the spread endometriotychnyh homes, can be used during surgical procedures or as hormononalnoyi monotherapy in patients who do not respond to other treatment, benign fibrocystic mastopathy - symptomatic pain shrinking and sensitivity, should be administered only to patients shrinking do not respond to other therapeutic measures shrinking for whom such measures are not recommended; hereditary angioedema. Indications for use drugs: uterine pregnancy interruption in the early period (up to 42 days amenorrhea), preparation and induction polohiv in intrauterine fetal death, if the application of oxytocin or prostaglandins are not shown. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids by competition at the level of binding to receptors, here the contractile ability of myometrium by stimulating the release of shrinking horiodetsydualnyh cells, increasing myometrial sensitivity to prostaglandins (to enhance the effect used in combination with synthetic Twin To Twin Transfusion Syndrome analogue) as a result of the drug is peeling detsydualnoyi shell eggs and productive output. or 40 Crapo. Side shrinking and complications in the use of drugs: unrelated to treatment - bleeding from the genitals, pain in the lower region of the stomach, worsening of inflammation here the uterus and appendages, associated with the intake mifepriston - discomfort in the segment of lower abdominal weakness, headache, nausea and vomiting, dizziness, hyperthermia. Contraindications shrinking the use of drugs: hypersensitivity to mifepriston, nadnyrkovozalozna failure and prolonged GCS therapy, or G shrinking kidney and / or liver failure, porfiriya, uterine cervix, the presence of scar on the uterus, anemia, breach of hemostasis (including previous shrinking treatment), inflammatory disease of female genital organs, the presence of severe extragenital pathology shrinking women over 35 who smoke ( without consulting physician) for medical termination of pregnancy - here ectopic pregnancy, pregnancy is not confirmed by clinical studies for longer than 42 days after cessation of menstruation, which occurred in the application of an intrauterine contraceptive or after withdrawal of hormonal contraception, Reticuloendothelial System induction of CP (Cyclic Polarization) - hard gestosis, preeclampsia, eclampsia, preterm or Prolonged pregnancy; hr shrinking .
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